ABC of Clinical Hematology 2nd ed - D. Provan (BMJ, Bio Med 1

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ABC OF
CLINICAL
HAEMATOLOGY:
Second Edition
Edited by
DREW PROVAN
BMJ Books
ABC OF
CLINICAL HAEMATOLOGY
Second Edition
 ABC OF
CLINICAL HAEMATOLOGY
Second Edition
Edited by
DREW PROVAN
Senior Lecturer, Department of Haematology, Bart’s and the London,
Queen Mary’s School of Medicine and Dentistry, London
© BMJ Books 2003
BMJ Books is an imprint of the BMJ Publishing Group
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system,
or transmitted, in any form or by any means, electronic, mechanical, photocopying,
recording and/or otherwise, without the prior written permission of the publishers.
First published in 1998
Second edition 2003
by BMJ Books, BMA House, Tavistock Square,
London WC1H 9JR
www.bmjbooks.com
British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library
ISBN 0 7279 16769
Typeset by Newgen Imaging Systems (P) Ltd., Chennai, India
Printed and bound in Spain by GraphyCems, Navarra
Cover image: False colour SEM of blood with myeloid leukaemia.
Robert Becker/Custom Medical Stock Photo/Science Photo Library.
 Contents
Contributors
vi
Preface
vii
1
Iron deficiency anaemia
1
Drew Provan
2
Macrocytic anaemias
5
Victor Hoffbrand, Drew Provan
3
The hereditary anaemias
9
David J Weatherall
4
Polycythaemia, essential thrombocythaemia, and myelofibrosis
14
George S Vassiliou, Anthony R Green
5
Chronic myeloid leukaemia
19
John Goldman
6
The acute leukaemias
23
T Everington, R J Liesner, A H Goldstone
7
Platelet disorders
28
R J Liesner, S J Machin
8
The myelodysplastic syndromes
33
David G Oscier
9
Multiple myeloma and related conditions
37
Charles R J Singer
10
Bleeding disorders, thrombosis, and anticoagulation
43
K K Hampton, F E Preston
11
Malignant lymphomas and chronic lymphocytic leukaemia
47
G M Mead
12
Blood and marrow stem cell transplantation
52
Andrew Duncombe
13
Haematological disorders at the extremes of life
57
Adrian C Newland, Tyrrell G J R Evans
14
Haematological emergencies
61
Drew Provan
15
The future of haematology: the impact of molecular biology and gene therapy
65
Adele K Fielding, Stephen J Russell
Index
71
v
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